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In the SCALE trial, patients receiving liraglutide lost an average 5.6 kg (~12 lbs) more than patients receiving placebo, which translated to a 5.4% body weight loss over the course of 56 weeks (NCT01272219)
That will not be the case in 2026
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Semaglutide works by mimicking a protein in your body called glucagon-like peptide 1, AKA GLP-1 - the same GLP-1 that keeps coming up all over the place lately, says Kunal Shah, an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center
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