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Moreover, we can simplify complex multi-group biological markers into standardized tests that can be implemented in clinical laboratories (such as a Western blot for protein detection or qPCR for gene detection)
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ICG-001, a preclinical agent, binding CBP and disrupting its interaction with -catenin, is efficacious killing tumour cells in both vitro experiments and mouse xenograft models of colon cancer and pancreatic ductal adenocarcinoma (PDAC)
The most notable of these potential complications would be insulin resistance and severe cardiovascular complications [R, R]
Kim DK, Han D, Bae J, Kim H, Lee S, Kim JS, Jeong YG, Shin J, Park HW
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