Its probably in the ballpark of what we expected
The disproportionate occurrence of GI AEs may have lead to unblinding and contributed bias to patient-reported outcomes such as HRQoL and safety outcomes
In addition, the data we have from members who have already discontinued a GLP-1 strongly suggests that when the cost (literal and figurative) outweighs the perceived benefit, patients opt out
Florio L, Lassi DLS, De Azevedo-Marques Perico C, Vignoli NG, Torales J, Ventriglio A, et al
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GLP-1s have become a popular topic because of their important role in appetite regulation, blood sugar balance, and overall metabolic health