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PDRN (polydeoxyribonucleotide) activates dermal adenosine A2A receptors to drive fibroblast activity, angiogenesis, and anti-melanogenesis

When fibre reaches the colon, its fermented by gut bacteria, producing short-chain fatty acids (SCFAs) like butyrate and propionate, which can trigger GLP-1 release

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in a study published in the European Journal of Endocrinology , which described it as the first selective growth hormone secretagogue (4)

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