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Side effects peak weeks 6-8
In particular, increased plasma insulin concentrations stimulate the gonadotropin releasing hormone (GnRH) pulsatility and potentiate the LH-dependent effect on the ovarian theca cells, leading to the enhanced synthesis of androgens and to the arrest of pre-antral follicle development [13]
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The results are presented as a fold increase compared with the sham group
Concurrently, levels of testosterone synthesis-related proteins CYP11A1 and CYP17A1 were significantly decreased in these senescent cells
It helps the body adjust and may reduce gastrointestinal side effects
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