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Weeks 2 to 4: Stronger responders notice physical changes, including better range of motion, fewer flare-ups, and the ability to handle more physical load

Given that CoQ 10 is an essential cofactor in the mitochondrial electron transport pathway, as well as a lipid-soluble antioxidant, it is reasonable to speculate that FSP1-CoQ 10 and ESCRT-III have complementary functions

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Following an apoptotic stimulus, Bax is activated and translocates to the mitochondria, where it undergoes a conformational change and inserts into the OMM