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Because these drugs work on the brains satiety centers, they support not just calorie restriction but longer-term behavioral changes that are key to sustainable health improvements

One candidate mechanism underlying this neuroprotective effect lies in the ability of metformin to improve insulin sensitivity, reduce chronic inflammation, and exert direct effects on brain cells [24]

A significant single predominant band was obtained when purification took place in the presence of PEGDA:GSH gels (Figure 4A, lane 5)

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Receptor-mediated cellular endocytosis and lysosomal degradation are important pathways for protein clearance