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Freeze-thaw cycles: if a validated frozen stock is used, make small aliquots and avoid repeated thawing

A major cause of CVD is atherosclerosis, a chronic inflammatory disease characterized by the pathogenic accumulation of vascular smooth muscle cells (VSMC), oxidized lipids and immune cells in the artery wall 2,3,4

Pappinen S, Pryazhnikov E, Khiroug L, Ericson MB, Yliperttula M, Urtti A

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are supported by binational FNR/DFG program: the FNR-CORE grant (C18/BM/12691266) and the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) project HI1400/3-1

It stimulates collagen and elastin production, supports angiogenesis, and promotes antioxidant and anti-inflammatory activity