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In preclinical models, chimeric antigen receptor (CAR)-macrophages (CAR-M) targeting the urokinase plasminogen activator receptor (uPAR), a cell-surface receptor upregulated in HSCs in cirrhotic human livers, demonstrated efficacy in reducing liver fibrosis (180)
Beyond the framework of diet and exercise, staying hydrated and getting enough rest are crucial aspects that shouldn't be overlooked
fragilis can activate Tregs to inhibit pro-inflammatory Th17 responses (90)
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Biochemical and Biophysical Research Communications Metabolomics of a mouse model of preeclampsia induced by overexpressing soluble fms-like tyrosine kinase 1
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