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In colorectal cancer, TP53-induced glycolysis regulatory phosphatase (TIGAR) drives resistance to erastin-induced ferroptosis via the ROS/AMPK/SCD1 pathway [71] , while inhibiting protein phosphatase 2 catalytic subunit alpha sensitizes these cells to ferroptosis by suppressing the AMPK/SCD1 axis [72]

J Biosci Bioeng 99, 303310

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