Protein purification Prior to each protein analysis the target protein has to be separated from a complex mixture to focus on the function without influences from other molecules, making protein purification to one of the main applications in biotechnology
10.1074/jbc.C400325200 J
Schizophr Res 84 : 214221
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Oral protocols use tablet-based dosing rather than reconstitution-based dosing, simplifying the protocol logistics considerably
Hence, a peptide was designed by substituting the negatively charged residues D42, D48, D49, E51, E56, and D57 within the p53 TAD PEP with alanine to increase its binding affinity to FOXO4 FHD and enhance membrane penetration