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2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D (13, 15, 16), but the potential weight lowering efficacy for this class of molecules first seen in rodents was not confirmed in humans until clinical trials with the first long-acting GLP-1 analogue, liraglutide (12)
Peptides are short chains of amino acids that serve as signaling molecules within the body
The Bottom Line ## Clinical Evidence Summary The evidence base for GHK-Cu spans preclinical and clinical research
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Key benefits of GHK-Cu include: Stimulating fibroblast cells to increase collagen and elastin production