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This avoids first-pass metabolism through the liver and the destructive GI environment

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The researchers demonstrated that intraduodenal infusion of metformin activated duodenal mucosal AMPK and lowered hepatic glucose production (HGP) in rat models of insulin resistance induced by a high-fat diet

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L -Propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector