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But It comes with significantly higher discontinuation rates A concerning rate of dysesthesia And potential cardiac safety issues that require further investigation The headline 28.7% weight loss is impressive but the real-world difference vs tirzepatide is only about 3% , and side effects may be more pronounced
Once reconstituted for research, it is kept at 28 C and typically used within 28 days
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individuals with certain allele combinations may require higher or lower effective doses to achieve the same metabolic result
Critics will ask: Why design REDEFINE-4 as an open-label trial
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