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These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism

D.BiswasS.et al (2015)

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Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the diabetes prevention program outcome study and the daqing diabetes prevention outcome study

Curr Opin Drug Discov Dev 6:675682 Griffin S, Clark JB, Canevari L (2005) Astrocyte-neurone communication following oxygen-glucose deprivation