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Animal-model topical studies have used solutions ranging from 0.05% to 0.2% (w/v)

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Model Rat, Achilles tendon-to-bone healing after surgical detachment Dose(s) reported 10 mcg/kg, 10 ng/kg, or 10 pg/kg per dose Route Intraperitoneal Duration Once daily from within 30 min of surgery, assessed to day 21 Model Rat, medial collateral ligament transection Dose(s) reported 10 ng/kg (IP)

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