Concerns have been raised that the rate of DKA in real-world practice would surpass rates seen in closely supervised RCTs [37]
Gut hormones-based pharmacology: novel formulations and future possibilities for metabolic disease therapy
Physical therapy remains valuable alongside peptide use
BCBS Massachusetts, BCBS Michigan, BCBS Vermont, Independence Blue Cross in Pennsylvania, Blue Cross of Idaho, and Highmark (which operates across Pennsylvania, West Virginia, New York, and Delaware) all implemented restrictions
Phase Cag introduction Weeks 9-12 Tirzepatide 5.0 mg/week (hold) Cagrilintide 0.25 mg/week Notes Add cagrilintide at the lowest dose
In addition, we did not provide robust evidence on the pharmacological mechanisms of the GLP-1 RA-related psychiatric AEs