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Cagrisema is Novo's next-generation combination therapy that pairs the GLP-1 receptor agonist semaglutide with the amylin analogue cagrilintide, and is considered central to the company's efforts to maintain its lead in the fast-growing obesity drug market
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Without the glucose-dependent insulin secretion and glucagon suppression provided by GLP-1 medications, HbA1c levels may begin to rise
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Over 72 weeks, adults with obesity were randomized to maximum tolerated doses of either tirzepatide (10 or 15 mg) or semaglutide (1.7 or 2.4 mg): Tirzepatide group: 20.2% mean body weight reduction Semaglutide group: 13.7% mean body weight reduction Tirzepatide also showed greater reduction in waist circumference: 18.4 cm vs
