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The LEAD-3 study found that liraglutide monotherapy reduced glycosylated hemoglobin (A1C), body weight, and blood pressure compared to glimepiride (36)
The STEP program (including STEP 1 and related trials) demonstrated clinically meaningful weight loss across populations and established semaglutide as a new standard for many patients with obesity
Trulicity Trulicity (dulaglutide) is not actually indicated for weight loss
Mol Endocrinol 11: 424-432, 1997
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