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Ashor AW, Siervo M, van der Velde F, Willis ND, Mathers JC
The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia
With coenzyme NADPH, GSSG is readily reduced to form two GSH molecules again
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12 If this combination is used, the patient should be closely monitored to determine linagliptin's efficacy
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