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A reduction of at least 40% in non-HDL cholesterol is the recommended target for treatment response
Questions to ask Can we start at a lower dose and adjust it slowly based on my response? What markers will we track to know if the dose is working? Whats the plan if I need to increase? How does this interact with my other medications? (Especially important if youre on HRT for menopause.) What to expect Many telehealth providers now offer low-dose GLP-1 programs
FDA-approved tirzepatide (Mounjaro and Zepbound) is supplied as a clear, colorless to slightly yellow solution in single-dose pens
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27 Importantly, GLP-1 action is short-lived, with a half-life of just 12 minutes in the bloodstream under normal physiological conditions, after which it is broken down by the enzyme dipeptidyl peptidase IV (DPP-4), resulting in a loss of its biological activity
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