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For people with severe obesity or obesity complicated by comorbid diseases, medications such as phentermine may be prescribed as an additional treatment to lifestyle modification therapy

Continuous exposure to any signaling molecule can lead to receptor downregulation, meaning the body responds less strongly over time

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B12 injections are typically administered either intramuscularly (IM) or subcutaneously, with common sites being the deltoid, thigh, or gluteal muscles

Inflammation may even be causing pain all on its own