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The Increlex label cites preclinical 2-year rat carcinogenicity studies in which increased mammary and skin tumor incidence occurred at high IGF-1 exposure

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thyroid, kidney, or liver dysfunction, skin rash, and complications with intravenous catheters such as infection and inflammation of the vein

Both of these nutrients are chemically similar, with only a minor difference in the atom arrangement

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Cytotoxic T cells (CTLs) and NK cellscritical antitumor effectorsare functionally impaired and undergo apoptosis under acidic pHe conditions, crippling host defenses (45)