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Refrigeration is recommended

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Here are some of the known benefits of B12: Your body needs B12 to produce healthy red blood cells

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StatPearls [Internet], 2023 June Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-ichi Okano, Hajime Isomoto, Yoshikazu Murawaki