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These highly unstable molecules are natural byproducts of cellular metabolism, but when left unchecked, they can cause severe oxidative damage to cellular membranes, proteins, and DNA

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Voltage-gated sodium channels were blocked by 0.5 M tetrodotoxin (TTX) (Tocris)

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Moderate exercise raises glutathione, but extreme endurance training without adequate recovery actually lowers it, so balance hard training days with active recovery (PubMed PMID: 29403072)