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4 At the cellular level, tumor cells can rewire survival signaling pathways, upregulate drug efflux transporters, undergo epithelial-mesenchymal transition (EMT), and enter dormant states
Published studies may describe observable responses within specific experimental models
These conversations usually overlap because many patients are not separating how they feel from how they look
Patients with persistent symptoms despite appropriate management may benefit from gastroenterology consultation
Additional trials in the TRIUMPH program may address retatrutide effects on cardiovascular outcomes, sleep apnea resolution, and kidney function, though these have not yet been formally announced
