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Putting pressure on your face can cause the Botox to move around under the skin, causing it to spread and take affect differently than intended

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However, the specific mechanisms behind these actions remain to be fully elucidated

For patients pursuing systemic regenerative or wound-healing protocols, injectables have a legitimate role under physician supervision, but if you are asking about wrinkles, skin firmness, or hair thinning, topical is the right delivery method