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INTRODUCTION Gahete et al

When semaglutide is compounded as a salt, it can affect its safety and efficacy and may lead to dosing errors or diminished efficacy

Some patients achieve 10% loss within 12 weeks, while others reach 25% over a longer timeline

Human thyroid C-cells appear to express GLP-1 receptors at lower levels than rodent C-cells, suggesting that humans may be less susceptible to GLP-1-mediated thyroid proliferation, though evidence on receptor expression varies

This mechanism is based on interaction with receptors in the brain, leading to the synchronization of brain waves

It also supports collagen synthesis, maintaining skin elasticity and firmness