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Purcell AR, Rodrigo N, Longfield MS, Glastras SJ

The mechanism the clinic describes is that MOTS-C works by activating AMPK, a key metabolic pathway involved in glucose utilisation, fat oxidation and insulin sensitivity

Eating something balanced is better than waiting until you feel perfect and then eating nothing

The improvements require ongoing treatment to maintain

Beyond age 18, medical eligibility depends on BMI, metabolic status, and absence of contraindications like personal or family history of thyroid cancer or multiple endocrine neoplasia

These hormone changes can affect periods in different ways, both helpful and disruptive