In studies, most nausea, diarrhea and vomiting occurred when people increased their dose but the effects generally decreased over time
The once-weekly injection schedule is another big plus
Apovian wasnt affiliated with the research
What did the SUMMIT trial demonstrate for tirzepatide
The study consists of a 12-week induction Phase followed by a 40-week maintenance Phase, with the primary outcome measuring clinical remission at Week 12 using mMS, while secondary outcomes include endoscopic improvement, clinical response, histological improvement, and various patient-reported outcomes
But here is the problem: PCOS itself creates metabolic barriers that make these interventions less effective than they would be in someone without the condition