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Methods Cell lines and human samples Human Burkitt lymphoma DG-75 (CRL-2625) and BL-2 (ACC-625), T-cell leukemia Jurkat (Clone E6-1, TIB-152), and HEK-293T (CRL-1573) cell lines were obtained from ATCC (LGC Standards S.L.U., Barcelona, Spain)
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Several factors, including genetics, sun exposure, and certain medical conditions can influence melanin production
After 4 weeks, they assess the patients tolerance and severity of side effects and adjust the dosage accordingly
Here, they undergo incomplete, alternative oxidation pathways that generate massive amounts of free radicals and reactive oxygen species (ROS), further damaging the delicate mitochondrial membranes and the very enzymes required for energy production
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