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Metformin has been demonstrated to prevent renal tubulointerstitial fibrosis (181) by addressing the reduced energy supply resulting from impaired fatty acid oxidation (FAO) in proximal tubular cells
Sodium-glucose co-transporter 2 (SGLT2) inhibitor canagliflozin suppresses TECs apoptosis via maintaining metabolic homeostasis (119), while boeravinone C, an PPAR activator/agonist, can alleviate lipid accumulation and inflammation, thereby suppressing tubular apoptosis (120)
The goal is to support energy, sleep, mood, libido, metabolism, strength, and long-term wellness through individualized care
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doi: 10.47102/annals-acadmedsg.2022358
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