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The medication increases the exposure of Levothyroxine by 33%

The NIHR Innovation Observatory states that it has no Marketing Authorisation in the EU/UK and remains in phase III development , which means it should be understood as an investigational medicine rather than a treatment clinicians can routinely deploy in standard practice (NIHR Innovation Observatory briefing on retatrutide)

Additionally, it slows down the emptying of the stomach, which contributes to a feeling of fullness and helps to control blood sugar levels

But the study tested a single dose, not the repeated weekly dosing that real-world treatment requires

For research use, it must be reconstituted with Bacteriostatic Water