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A recent Cornell University report found the share of US households reporting at least one GLP-1 user rose from around 11% in late 2023 to more than 16% by mid-2024

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Future multicenter, large-sample RCTs incorporating liver transcriptomics and metabolomics are warranted to optimize dosing and treatment duration in MASLD patients with IR

Meanwhile, research on the mechanism and efficacy of GLP-1R/GIPR dual agonists and GLP-1R/GIPR/GCGR triple agonists paves the way to a ground-breaking therapy specific for obesity, which suggests multi-target drugs may have more advantages than a single target