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This immunoregulatory molecule suppresses immune activation in epithelial cells by specifically inhibiting TLR2-mediated IL-8 production in airway epithelium upon engagement with its endogenous ligand CEACAM8
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Previous reports have also shown that GLP-1 treatment can reduce locomotor activity [52, 53]
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10.1161/01.ATV.0000217611.81085.c5
Studies in mice suggest that GIP may potentiate the GLP-1-induced reduction of food intake and body weight by enhancing POMC expression and neuronal activation within distinct neuron populations in the hypothalamus (149)
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