Furthermore, epithalon has been shown to restore the circadian rhythm of cortisol levels and melatonin production by the pineal gland, leading to better sleep quality
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Specifically, in the MAFLD rat model, dysbiosis of the gut microbiota can lead to impaired intestinal barrier function 48,49,50
Additionally, patients with Multiple Endocrine Neoplasia syndrome type 2 should not receive tirzepatide due to the theoretical increased risk of medullary thyroid carcinoma associated with this genetic condition
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