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Wennberg, J

The approval was based on the SELECT trial (Lincoff et al., New England Journal of Medicine 2023), enrolling 17,604 patients with established cardiovascular disease

Thats a 7000 calorie deficit per week

In another study in volume-loaded participants, GLP-1 induced natriuresis together with the ANG II level decrease, independent of renal hemodynamics (renal plasma flow, GFR unchanged) and renin concentrations 37

Chemically, polyphenols are phenolic compounds classified based on their structure and substituents [49]