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A lower all-cause dementia risk associated with SGLT2 inhibitors was found among those with atherosclerotic cardiovascular disease (HR [95% CI]: 0.80 [0.680.95]) and renal insufficiency (HR [95% CI]: 0.80 [0.650.99])

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Simvastatin differentially modulates glial functions in cultured cortical and hypothalamic astrocytes derived from interferon / receptor knockout mice

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Laboratory and Physiological Parameters Modest dose-dependent increases in heart rate (typically 27 beats per minute) were observed, similar to other incretin-based agents