Proton-pump inhibitors, such as pantoprazole, are commonly used to treat various gastrointestinal diseases in elderly patients
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Animal studies report the doses given and the outcomes, but not the plasma pharmacokinetics
However, natural glutathione synthesis in these cells relies on the recycling of its constituents, and as a consequence, the increase in glutathione circulating in the blood can still support this process
Inhibition of glutathione S-transferase 3-3 by glutathione derivatives that bind [PMID: 1883342] Laboratory literature summary: Inhibition of glutathione S-transferase 3-3 by glutathione derivatives that bind covalently to the active site
When delivered via a rectal suppository, glutathione may offer therapeutic benefits for individuals suffering from conditions that involve oxidative stress