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Limitations Limitations of our study include a small sample size and limited number of brain regions examined
Drugs are not metabolized by the liver, but multidrug and toxin extrusion protein 1 (MATE1) expressed in hepatocytes is involved in the clearance of drugs, which is transported to the kidney through bile or through blood (Gong et al., 2012)
In a clinical trial, combination therapy with liraglutide and metformin shows significantly greater weight loss and lower incidence of hypoglycaemia, as compared to combination therapy with glimepiride and metformin 12,13
Precautions Consult a healthcare professional before use, particularly if pregnant, breastfeeding, or taking medications/supplements, or if you have a medical condition
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