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Adjusting your dose or lifestyle might help, but some people may not respond well to the medication
Every retatrutide trial so far used once-weekly dosing, so the safety and effectiveness of any split schedule come from pharmacokinetic modelling and self-reported community experience, not trial data
In clinical trials, peak weight loss on tirzepatide occurred by 9 months
However, research has shown that this process is disrupted during injury and disease
BMJ 2021;372:m4573
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