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Both diarrhea (33.3% at 12 mg) and constipation (16.7% at 12 mg) were reported in Phase 2, and both can produce lower abdominal cramping through different mechanisms researchers sometimes describe this presentation as retatrutide gas pain or trapped-gas-style pressure rather than classic stomach cramps
Every peptide undergoes rigorous third-party laboratory testing using advanced techniques like HPLC, LC-MS, and NMR
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