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Future directions should prioritize RCTs targeting early-stage glaucoma, with primary endpoints encompassing both structural (e.g., OCT-based RGC metrics) and functional (e.g., visual field preservation) outcomes, to validate the potential of GLP-1RAs as a true disease-modifying strategy in glaucoma management

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Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2018

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Hean AC et al

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Whats real: NAD biology is scientifically valid

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Valence specificity If GLP-1 RAs attenuate neural responses to both appetitive and aversive stimuli, this pattern could indicate a generalized dampening of emotional reactivity

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Singh S, Khera R, Allen AM, Murad MH, Loomba R

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