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One thing that I reflect on and consider is that even some of the early anti-amyloid therapies that ultimately failed to slow disease progression did show some change in the Alzheimers biomarkers, she told Being Patient

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These multisystem benefits create a healthcare ROI calculation where GLP-1 therapy prevents conditions with substantially higher lifetime treatment costs than the drug itself

doi: 10.1016/0031-9384(90)90144-S 30 CohenITSherwinBBFlemingAS

This could include high blood pressure, type 2 diabetes or high cholesterol

It correlates more strongly with the severity and spread of symptomatology than A plaque deposition, has a stronger association with future cognitive stage than A plaque deposition or MRI markers, and can predict the response to anti-A monoclonal antibodies