97 found that isocaloric protein restriction down to 12E% over 3 months was not able to reproduce the beneficial metabolic changes induced by CR in male C57BL/6 mice, in particular the decrease in IGF-1 concentrations
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The results were notable: Dendritic length increased Branching complexity rose Total junction counts went up, indicating enhanced synaptic connectivity and plasticity Figure 3
Ward A, Tardiff S, Dye C, Arrighi HM