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GLP-1 medications bind to GLP-1 receptors in the pancreas, stimulating glucose-dependent insulin secretion whilst simultaneously suppressing glucagon release in a glucose-dependent manner
GLP-1Rmediated transport occurs through circumventricular organs (CVOs) and maybe other parts of the hypothalamus via fenestrated capillaries and is partially dependent on tanycytemediated transport through certain localized compartments of the cerebrospinal fluid (CSF)
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The skin should be washed with mild soap and water, then thoroughly driedavoiding lotions, oils, or powders that could interfere with adhesion
