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CAR 16, 261277
In the SUSTAIN 6 cardiovascular outcomes trial (published in NEJM 2016), semaglutide reduced the risk of major adverse cardiovascular events (MACE) by 26% compared to placebo in patients with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors
In type 1 diabetes mellitus, which involves autoimmune -cell destruction, adjunctive therapy with GLP-1RA has shown promise in patients with residual -cell function
10, 2018) and the European Heart Journal (Dec
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