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B12 administration may cause rapid optic atrophy in these patients Have polycythemia vera
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For others, it may take a few weeks for the results to become evident
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Studies show that 5-amino-1-methylquinolinium injection inhibits NNMT, normalizes nicotinamide metabolism, elevates NAD+, reduces oxidative stress in cells, suppresses apoptosis, preserves cell function, and promotes insulin secretion, supporting longterm glycemic control