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That narrow approval gives tesamorelin stronger clinical context than most GH-related research peptides

Moreover, both doses of the acylated ligand exerted a larger anti-hyperglycaemic effect in an intra-peritoneal glucose tolerance test performed 72 hours after dosing (Figure 5F)

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Over time, beta-cell workload diminishes, allowing functional recovery and preservation of beta-cell mass through reduced apoptosis and improved insulin secretory dynamics

Two reasons explain that

The medication's effects on weight, glucose metabolism, and lipids may collectively contribute to reducing cardiovascular risk in this population, though dedicated treatments for each component of metabolic syndrome remain important